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Dr. Daniel Amen, after scanning 250,000 brains: “This is what negative thinking does to you”

Warren van der Sandt by Warren van der Sandt
March 20, 2026
in Human Science
How negative thinking affects us

Credits: Kenny Eliason, The Pulse Internal edition

Negative thinking has a direct impact on our health.

As our scientific prowess enhances, we are making revolutionary discoveries that will impact our overall health and the medical sector. Human brains are complex and require extensive studies to get to the bottom of our most challenging questions. And Dr. Daniel Amen has studied many, many brains.

How often do negative thoughts creep into your brain?

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How medical science has transformed the way we look at ourselves

For a significantly large portion of our human history, illness of any kind was seen as a spiritual punishment for wrongdoings.

Thankfully, that theory has been replaced by modern biology, which proves we are nothing more than a set of interconnected systems and parts working together in a symphony of science.

Before the invention of X-rays and MRIs, much of what took place inside our bodies and brains was unable to be observed.

We used to believe that our brains were the single factor that influenced our personality. Science has taught us that our gut microbiome also plays a vital role in determining our immunity, appetite, and even our moods.

Revelations in human science have rewritten our history as a species

Human science has come an exceedingly long way in a very short time frame.

Thanks to the new studies and medical science breakthroughs that have become a much more regular occurrence, we have transformed the human science sector. Through wearable tech, we are now tracking nearly every aspect of our health in real time.

We now understand that our brains can actually rewire themselves at any age with a little bit of effort on our part.

Medical science has seen the overall life expectancy of us as humans doubling over the last 200 years. Centuries ago, the average life expectancy was 32 years, but with the advent of modern medicine, it has risen to about 72 years.

The microplastics that have become a factor in nearly everything we eat and drink have raised alarm bells for medical experts as we now understand their impact.

However, on the recent full podcast with Dr. Daniel Amen, the Diary of a CEO host was in for a shock as the truth behind our negative thoughts has been revealed. And it’s astonishing to say the least.

Negative thoughts have a direct impact on our physiology

The Diary of a CEO podcast has become one of the most popular on the internet in recent years.

The host, Steven Bartlett, has become a major figure in the global economy due to the unique and insightful guests that feature on his podcast. He has even featured on the UK version of “Shark Tank.”

In a recent episode, Dr. Daniel Amen has made a startling admission after studying over 250,000 brains.

Recent medical breakthroughs have proven that we actually have a third control center in our bodies besides our brains and guts. But this announcement from Dr. Amen has revealed the truth about what happens at the moment when negative thinking creeps into our minds.

How bad and intrusive thoughts affect your brain chemistry

The doctor found that at the exact moment when we begin to have negative thoughts, our brains release specific chemicals into our bloodstream that immediately make us feel terrible.

He found that negative thoughts can “pollute” our internal ecosystem.

He proposed methods to keep calm and push out the impacts of these negative thoughts. He stated that negative thoughts can be addressed to “lighten up our lives and thought processes.” But consistent negative thinking can lead to a world of mental health issues like Alzheimer’s.

We have mostly relied on controversial treatments like electroshock therapy to address serious mental issues.

But Dr. Amen has noted that we are in full control of our brains and with a little bit of mental toughness and effort, we can avoid the automatic negative thoughts in our brains.

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